The Laboratory for Genomic Research (LGR) is a new functional genomics center on the UCSF Mission Bay campus in San Francisco, CA, representing a novel hybrid model that brings together researchers from UC Berkeley, UC San Francisco, and GlaxoSmithKline under a single roof, working on projects both together and independently. The new laboratory will house up to 40 scientists, working in close partnership to develop and apply CRISPR-Cas based functional genomics tools to collaborative research projects. The goal of the LGR's work is to develop facilitating CRISPR technology, identify new drug targets, and understand biological mechanisms to foster advances across the field.
Basic Qualifications:
• Master’s degree with 10 years of experience or Doctoral degree in the natural sciences or other relevant degree (biology or chemistry preferred)
• Expertise in any of the following (a combination of skillsets preferred):
o functional genomics screening (CRISPR/Cas9 a plus) in mammalian systems
o next-generation sequencing (single cell sequencing a plus)
o complex cellular models including primary cell types, iPSCs, 3D spheroids/organoids
o advanced imaging techniques including confocal microscope, flow cytometry
o computational biology and data analytics
o laboratory automation
Preferred Qualifications:
• experience with genome editing or functional genomics screening
• background in oncology or immunology, ideal
• expertise in advanced cellular models including primary cell types, iPSCs, 3D spheroids/organoids
• fluency across a multitude of scientific techniques including genetic, proteomic, imaging, and/or other 'omics technologies
• fluency with high content imaging
• project leadership experience
• proactively identifies and resolves issues and hurdles
• comfortable defining new ways of working in an ambiguous environment
• strong track record of delivery
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Organization Details
Known as the Laboratory for Genomic Research (LGR), the partnership will be headed by Dr. Hal Barron, Chief Scientific Officer and President, R&D, at GSK; UCSF’s Jonathan Weissman, PhD, Professor of Cellular and Molecular Pharmacology, who has pioneered new applications of CRISPR for biological research; and CRISPR co-inventor Jennifer Doudna, PhD, Professor of Biochemistry, Biophysics, and Structural Biology at UC Berkeley.
The LGR is located at 499 Illinois Street in San Francisco's Mission Bay and is now open and recruiting scientists of diverse backgrounds and skillsets.