UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. Postdoctoral Scholars will be eligible for generous benefits including supplemented health insurance and University housing in San Francisco https://postdocs.ucsf.edu/benefits.

The Martens Lab at the University of California, San Francisco (https://profiles.ucsf.edu/hanna.martens) is seeking postdoctoral researchers to lead projects focused on uncovering the fundamental mechanisms of physiological aging. The lab is particularly interested in investigating the key roles of tissue mechanics and innate immune signaling in shaping aging-related outcomes (Sladitschek-Martens et al., YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS–STING, Nature, 2022). By leveraging genetic mouse models, single-cell and spatial transcriptomics, imaging, mechanobiology assays, and flow cytometry, we explore how load-bearing structural cells contribute to maintaining youthful organ homeostasis and aim to identify the cellular and molecular mechanisms that drive the progressive breakdown of connective tissue mechanics with age.  

Key Responsibilities:

• Lead an interdisciplinary research project integrating biophysics, immunology, and aging biology.
• Design and execute experiments using genetic mouse models, single-cell RNA sequencing, flow cytometry, imaging, histology, and data analysis.