The Mordes Lab at UCSF (mordeslab.ucsf.edu) is seeking a highly motivated post-doctoral fellow to study mechanisms of neurodegeneration in dementia, movement disorders, and related diseases using human stem cell-derived neurons and patient brain samples.
The main goals of our research are to develop new models of neurodegenerative diseases and to identify new therapeutic targets. We study the function of proteins that are associated with amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Parkinson’s disease (PD) and involved in RNA processing, autophagy, and lysosomal biology. We routinely generate human excitatory neurons from cultured stem cells and incorporate neuropathology approaches. The Mordes Lab is part of the Institute for Neurodegenerative Diseases (https://ind.ucsf.edu/postdoctoral-fellows-program) and the Weill Institute for Neurosciences.
The post-doctoral fellow will engage in dynamic projects on neurodegenerative diseases that utilize single-cell analyses of neurons, isogenic human pluripotent stem cells, RNA-sequencing, and global proteomics, and prepare results for formal presentations and publications.
Required:
Recent PhD or MD in the biomedical sciences or related fields
Background in core molecular and cellular biology
Ability to independently conduct experiments and perform data analysis, and collaborate effectively with lab members
Record of research publication
Preferred:
Strong interest in neurobiology or neurodegenerative disease
Experience in computational biology and analysis of large (“omics”) data
Excellent communication skills
Post-doctoral fellow salary and benefits are based on experience and the UC scale (https://postdocs.ucsf.edu/pay-and-benefits)
Please send CV (or biosketch) and biref statement of research interests to:
Dr. Mordes at [email protected]
The University of California San Francisco is an equal opportunity employer.