Specialist – Molecular Biology & Proteomics (Krogan lab, UCSF)

1700 4th St
Byers Hall, rm BH-309
San Francisco, CA 94158
United States
Job Posted Date: 
June 6, 2023
Academic Positions
Full-time Positions
Life Sciences

Your work will focus on mapping protein interactions and signaling networks for complex biological problems on cross-disciplinary projects.

This role is an excellent opportunity to learn several valuable, cutting-edge techniques in cell and molecular biology, as well as proteomics, while working with a dynamic and interdisciplinary research team. You will generate and characterize cell lines and/or iPSC lines expressing affinity-tagged proteins of interest, perform affinity purifications, and proximity labeling of proteins and their interactors for mass spectrometry analysis to study protein-protein interactions. You will learn and apply different cellular, molecular and biochemical assays to validate these findings. The candidate will also have the opportunity to develop and implement new protocols for mass spectrometry-based proteomics experiments.

The Krogan Lab is a highly dynamic and collaborative laboratory focusing on the molecular networks underpinning infectious disease, carcinogenesis and neurological disorders.

Our ideal applicant is a problem solver with a positive attitude, excellent organizational and interpersonal skills, and the ability to learn and implement methodology efficiently. Candidate’s CV and/or cover letter must state basic qualifications (or if pending) upon submission. Candidates must meet all qualifications by the time of hire.

Job Requirements: 

Preferred Qualifications:

  • Experience generating new cell lines and characterizing them.
  • Experience culturing iPSCs and iPSC-derived cells.
  • Experience transfection or viral transduction.
  • Experience with affinity purifications of proteins.
  • Experience with CRISPR/gene editing techniques
  • Experience with immunoprecipitation.
  • Experience in preparation of samples for mass spectrometric analysis.
  • Experience in fluorescence microscopy.
  • Experience with mass spectrometry data.
  • Experience with managing large datasets and/or databases.
  • Experience with statistical data analysis.

To apply, please submit a CV, cover letter, and the contact information for 2 references to https://aprecruit.ucsf.edu/JPF04558

See Table 24B for the salary range for this position. A reasonable estimate for this position is $49,000 -$173,900.

How to Apply: 

Document requirements

Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.). 

Cover Letter

Reference requirements

  • 2 required (contact information only)
San Francisco
Greater Bay Area