Position Description:
Calico is seeking a highly motivated scientist to join and lead discovery research projects in the metabolism of aging group. Specifically, we are interested in applicants with a long-term interest in understanding metabolic mechanisms in normal physiology and pathology, including cancer. We seek expertise in combining cutting-edge molecular and biochemical techniques, including transcriptomics and metabolomics, with in vitro and in vivo models to uncover metabolic interactions in health and disease. Join our collaborative, cross-functional environment at the forefront of aging research, work alongside world-class technology labs, and lead ambitious research projects that could transform our understanding of aging.
Responsibilities:
- Perform basic research to determine metabolic mechanisms underlying aging process
- Develop approaches to evaluate metabolic interactions between specific cell types during aging
- Publish papers and present findings both internally and at scientific conferences
Position Requirements:
- PhD or MD/PhD in cell/molecular biology, biochemistry or a related field with 0-5 years of postdoctoral and/or industry experience
- Experience working with animal models to study human disease and/or aging
- Deep knowledge of cellular and organismal metabolism and physiology
- Strong working knowledge of genetics, cell biology and molecular genetics
- Detail-oriented, organized and driven
- A track record of strong research productivity
- Strong teamwork and communication skills
- Flexible, able to respond quickly to shifting priorities and able to multitask
- Must be willing to work onsite five days per week
Nice to Have:
- Experience with mass spectrometry to measure metabolites and/or lipids and/or proteins
- Experience using stable isotope labeling to understand metabolic fluxes in vitro and/or in vivo
- Experience with integrating multiomics data
- Expertise in immune biology and immune cell cultures
- Competence with mammalian tissue culture, in vitro gene editing techniques (CRISPR/Cas9, viral transduction) and basic molecular biology methods
- Familiarity with R or Python for data analysis and visualization
The estimated base salary range for this role is $127,000 - $155,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.
Organization Details
