Jennifer Doudna and Benjamin Rubin are recruiting a jointly supervised postdoc to work on in situ DNA editing of microbiomes at UC Berkeley. The candidate will join a highly collaborative team of researchers in the two labs, who are tightly integrated with the broader Innovative Genomics Institute’s Microbiome Editing Initiative. Projects will build on proof-of-principle community editing experiments to enact precise and efficient modification of microbiome members. This work relies on developing and using novel CRISPR-Cas editing systems, sequence-based tracking of edits, and next-generation tools for in situ control of edited organisms. The postdoc will collaborate with a multidisciplinary group from UCSF, LBNL, JBEI, and Cedar-Sinai to apply microbiome editing to understand and control impactful microbial communities such as those in the human gut, cow rumen, and the rhizosphere. Specific projects range from identifying and modifying microbes with causal roles in inflammatory bowel disease and asthma, to mitigating methane emissions from livestock.
https://aprecruit.berkeley.edu/JPF03866