Several projects and opportunities are available including the general themes of: understanding how the microenvironment and other external factors influences progression, determining the how the microenvironment drives genomic evolution, further understanding the ‘omic’ makeup of Barrett’s esophagus and gastric metaplasia, using this genomic knowledge to understand how these alterations cause progression into invasive cancer, and using the above information to build biomarker assays for better risk stratification and treatment algorithms. In addition, the person who fills this position will be highly encouraged to explore their own new ideas.
The postdoctoral researcher will work closely with the laboratory PI, Matthew Stachler, as well as the many collaborators within and external to UCSF and help direct the research specialists and technicians within the lab. They will be encouraged to present at scientific conferences and apply for funding opportunities when appropriate.
Some of the many technologies/techniques we utilize within laboratory include: a wide variety of omic technologies (single cell DNA and RNA seq, methylation, spatially defined transcriptome analysis, and others), highly multiplex imaging, primary human cell culture/models, and a murine model of gastroesophageal metaplasia.
For more information on our laboratory please visit our laboratory website at http://stachlerlab.ucsf.edu/.
A MD or PhD in a relevant field is required. The person who fills this position must be enthusiastic, self-motivated, and independent while still willing to ask for guidance when needed. Experience in tissue culture is required, and experience with organoid and/or other 3D culturing techniques is a plus. Depending on the project(s) selected to work on, an established understanding of the techniques used is desired and a willingness to learn is a must. Previous experience in genomics, cancer biology, or pathology is desired. Understanding of programing and bioinformatics is also a plus but not required.[email protected]
To apply or for more information email [email protected]. To apply please send cover letter, CV, and contact information for at least two references.