Postdoctoral Research Fellow–Immunotherapeutic Design

Location: 
La Jolla, CA 92121
United States
Job Posted Date: 
January 20, 2021
Opportunities: 
Full-time Positions
Population: 
Life Sciences

ROLE RESPONSIBILITIES

  • Expression of MHC I alleles and refolding with designed peptides using established refolding methods
  • Structure determination of MHCI-peptide complexes using X-ray crystallography
  • Measuring NK cell activation using cytotoxicity assays
  • Staining of CD8+ T cells and NK cells using flow cytometry 
  • Dissemination of results via peer-reviewed publications and presentations

BASIC QUALIFICATIONS

  • Recent PhD in Immunology, Biochemistry, or related discipline with first author publication(s) in peer-reviewed and internationally renowned journals
  • Technical expertise in protein expression and purification, as well as protein crystallography.
  • Cell-culture, cytotoxicity assays (e.g DELFIA immunoassay)
  • The ability to plan and execute experiments independently

PREFERRED QUALIFICATIONS

  • Reporter cell line generation (YTS and 293T cells)
  • Flow cytometry experience
  • Protein binding kinetics (SPR, BLI)
  • Strong understanding of immunology.
  • Motivated, proactive, and eager to learn.
  • Excellent communication and presentation skills.
  • Advanced molecular design proficiency.

Additional Details:

  • Eligible for Employee Referral Bonus
  • Eligible for Relocation Package Benefit
How to Apply: 

https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---California---La-Jolla/Postdoctoral-Fellow-Immunotherapeutic-Design_4782170

 

Location: 
California