Postdoc opportunity - Neurophysiology of Non motor symptoms in Parkinson's using sensing enabled pacemakers - LittleLab

United States
Job Posted Date: 
September 19, 2022
Postdoc Positions

Dr Simon Little ( is seeking a talented postdoctoral student to study the neurophysiology of motivation and non motor symptoms in Parkinson's disease using sensing-enabled, deep brain stimulator pacemakers towards automated optimization of adaptive, personalized, brain stimulation. 

Dr Little and his lab (plus collaborators including Phil Starr) have pioneered adaptive deep brain stimulation and chronic neural sensing for movement disorders and are now working at the forefront of studies to develop personalized stimulation therapies for patients. This includes research to understand the link between cortico-basal network physiology and fundamental behavior, physiological biomarker discovery and testing of closed-loop stimulation strategies for neurological patients.

The lab presents here an exciting opportunity to work with next generation technology that can continously record and stream intracranial cortical and basal ganglia physiology remotely from patients, in their homes, over multiple days. This will enable longitudinal, remote, recordings from patients in the naturalistic environment to investigate the relationship between neural signals motivation and sleep. The project will use remote experimental behavioral paradigms and wearable tracking techology to measure clinical state of patients in their naturalistic environment. This will be paired with chronic recordings from the basal ganglia in patients homes. Cognitive neuroscience, signals analysis, statistical methods will be particularly useful.

Job Requirements: 

Job Requirements: 


PhD in Neuroscience, Neuro - engineering or related disciplines. 

Advanced analytical and problem solving skills

Excellent, leadership, project management and communication skills

Ability to independently run experiments, analyze data and plan forward strategy combined with excellent team and collaborative working skills

Highly self-motivated, inquisitive scientist

Record of publication in peer-reviewed journals


Experience in neurophysiological analysis and strong analysis skills (Matlab / Python) would be highly beneficial.

Control systems and machine learning experience.

How to Apply: 

How to Apply: 

Apply by sending the following to Simon Little ([email protected])

  • Current CV
  • Cover letter describing interst and relevant experience for the project. 
  • Three potential reference contacts

We look forward to hearing from you.

San Francisco
Greater Bay Area