The Shum lab at UCSF is recruiting talented and highly motivated individuals to join our team as a Postdoctoral Research Scholar. We are members of the UCSF Immunology Program, Biomedical Sciences (BMS) Graduate Program and the Cardiovascular Research Institute (CVRI). Located on the vibrant and beautiful UCSF Mission Bay Campus, we investigate rare Mendelian disorders of immune dysregulation in humans and mice and seek to unravel fundamental cellular and molecular mechanisms of disease. Current projects are focused on STING signaling in the context of autoimmunity and cancer immunotherapy. Experience in cellular immunology, multi-color flow cytometry, and molecular and cellular immunology is required. Candidates must have a recent PhD in immunology, cell or molecular biology or related fields. Interested applicants should submit to Dr. Anthony Shum by email at [email protected]:

1. Cover letter outlining research accomplishments
2. CV
3. List of 3 references with contact information including mailing address, phone number and e-mail address.

Publications by the Shum lab include:

• Homeostatic regulation of STING by retrograde membrane traffic to the ER. Nature Communications. 2021 01 04; 12(1):61.
• A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome. Journal of Experimental Medicine. 2020 11 02; 217(11).
• A Defect in Thymic Tolerance Causes T Cell-Mediated Autoimmunity in a Murine Model of COPA Syndrome. Journal of Immunology. 2020 05 01; 204(9):2360-2373.
• COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nature Genetics. 2015 Jun; 47(6):654-60.