Full-time Postdoctoral Research Position - UCSF Hematology Oncology

A Full-time Post-doctoral research position is immediately available for a highly motivated individual wanting to apply for graduate training in the biological sciences and immunology to study immunotherapeutic approaches to hematologic malignancies. The position in the Gaensler Lab in the Helen Diller Comprehensive Cancer Center/ Division of Hematology/Oncology at UCSF is in a vibrant and exciting environment where cross-cutting programs, including the Bakar ImmunoX Initiative, the Cancer Immunotherapy Program, and groups belonging to the Parker Institute for Cancer Immunotherapy are situated. The candidate must have excellent recent training and research experience in molecular/cellular biology and immunology or a related discipline.  We are pursuing translational and pre-clinical studies using a novel leukemia vaccine (Shi et al., 2018). Currently, the outcomes for older patients with acute myelogenous leukemia are dismal. Thus, our long-term objective is to enhance patients' anti-leukemic immune responses, thereby increasing relapse-free survival. Proof of concept studies has been performed in relevant cell lines and in vivo in tumor model systems (Shi et al., 2018). We are assessing immunological responses to engineered human leukemia vaccines in preparation for an IND application. We are also pursuing collaborative mechanistic studies with UCSF, UCLA, and other labs. Individuals interested in basic and translational cancer research and with a strong background in cellular biology, immunology, or bioinformatics, and murine models of human disease are encouraged to apply.