Encoded Therapeutics Inc. is a biotechnology company advancing precision medicines for a broad range of genetic disorders. Our mission is to unlock new opportunities for viral gene therapy through genomics-driven discovery. We focus on delivering life-changing advances for individuals with genetic disorders not addressable with current approaches. For more information, please visit www.Encoded.com
We are recruiting a Computational Biology Intern to join our Technology team full time for summer 2022. The Technology team is developing novel sequencing-based assays to screen through millions of potential gene therapy candidates. Currently, our team is using single nucleus RNA-seq to understand gene therapy candidates at a single-cell resolution. You will be helping our bioinformatics team build pipelines to analyze this data, quantify cell-level activity and specificity for promising candidates, and visualize key insights.
This is a unique opportunity to work at the intersection of genomics and computing and participate in the development of a diverse therapeutic pipeline driven by a transformative core technology. We are looking for someone with a strong working knowledge of software engineering and next-generation sequencing (NGS) technologies, single nucleus RNA-seq in particular.
Responsibilities
- Analyze single nucleus RNA-seq datasets (10X) to determine specificity and potency of screened candidates in cell types of interest
- Visualize and communicate findings to key stakeholders
- Enrolled full-time or part-time in an accredited college or university in an undergraduate, graduate, or doctoral degree program in computer science, bioinformatics, genomics, Computational Biology or similar field
- Experience programming in a high-level language, such as Python or R
- Strong background and understanding of NGS technologies and single nucleus and/or single cell RNA-seq
- Experience with version control (e.g. GitHub)
- Familiarity with cloud computing infrastructures on AWS and working with cloud-based tools such as AWS Batch, S3, and Sagemaker is a plus
- Experience with visualization tools such as Superset, Tableau, matplotlib, ggplot2, or TIBCO Spotfire is a plus
Encoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Encoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate. Encoded will not tolerate discrimination or harassment based on any of these characteristics. Encoded encourages applicants of all ages.
If you need assistance or an accommodation due to a disability, you may call us at +1 650-491-0272.
Please email the hiring manager directly. Serena Liu: [email protected]
Organization Details
